Endocrine Abstracts

The use of 24 h urinary 5-hydroxyindolacetic acid (5-HIAA) concentrations to detect carcinoid patients is a well established procedure while random urinary 5-hydroxyindolacetic acid/creatinine ratio (5-HIAA/cr) may also offer a simpler approach in the diagnosis of carcinoid tumours. However, there is uncertainty regarding the ability of these tests to offer a prognostic indicator for patients.We retrospectively reviewed the initial paired urinary 5-HIAA/...

Although 24 h urinary 5-hydroxyindolacetic acid (5-HIAA) concentration is a well established test for the detection and monitoring of carcinoid tumours, compliance, adequacy of collection and the influence of dietary sources of serotonin are problems associated with this approach. Recently, a random urinary 5-hydroxyindolacetic acid creatinine ratio (R/5-HIAA/cr) test has become available which can be used in outpatient departments, however its correlation to 24 h 5-HIAA (24/5...